UNUSUAL BEHAVIOUR OF PAPILLARY THYROID CARCINOMA IN AN OTHERWISE FAVOURABLE VARIANT

Abstract

Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy in iodine replete area. There are twelve variants of PTC of which classic and follicular variant (FV) are the most common (>90%) and are associated with very good prognosis. Three cases of aggressive behaviour of PTC are discussed in this case report. Moreover, we searched the literature for possible explanation with emphasis on molecular study and the impact thereof on the American joint committee on cancer (AJCC) classification.